TITF-1 abnormalities in NSCLC 1 Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: Implications in lung cancer pathogenesis and prognosis
نویسندگان
چکیده
Departments of Thoracic/Head and Neck Medical Oncology, Pathology, Biostatistics and Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas. The Hamon Center for Therapeutic Oncology Research and Department of Pathology, The University of Texas Southwestern Medical Center, Dallas, Texas. 7Department of Medicine/Medical Oncology and Pathology, The University of Colorado Cancer Center, Aurora, Colorado. † To whom correspondence should be addressed: Ignacio I. Wistuba, M.D., Departments of Pathology and Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Tel: 713-563-9184, Fax: 713-563-1848, Email: [email protected].
منابع مشابه
Imaging, Diagnosis, Prognosis Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis
Purpose: Emerging evidence suggests that aberrant expression of oncogenes contributes to development of lung malignancy. The thyroid transcription factor 1 (TITF-1) gene functions as a lineage survival gene abnormally expressed in a significant fraction of non–small cell lung cancers (NSCLC), in particular lung
متن کاملAbnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis.
PURPOSE Emerging evidence suggests that aberrant expression of oncogenes contributes to development of lung malignancy. The thyroid transcription factor 1 (TITF-1) gene functions as a lineage survival gene abnormally expressed in a significant fraction of non-small cell lung cancers (NSCLC), in particular lung adenocarcinomas. EXPERIMENTAL DESIGN To better characterize TITF-1 abnormality patt...
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تاریخ انتشار 2010